Textbook of Head and Neck Pathology by Margaret S. Brandwein

Author:Margaret S. Brandwein
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham

Approximately 20 % of EFT are variants (Atypical EFT), which may be associated with poorer prognosis [128]. Confirmation of EWS-FLI1 fusion can be especially useful for this group below: Large cell/anaplastic EFT is composed of tumor cells with large nuclei, prominent nucleoli, anaplasia, abundant pink cytoplasm, and binucleate cells.

Spindled variant EFT contains greater degree of spindling and well-developed vasculature.

Sclerosing variant EFT contains abundant, hyalinized, eosinophilic stroma.

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